research Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by the Increase of Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps
IL-6 from stem cells helps repair skin and grow hair.
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research BCL-2 and Bax Expression in Skin Flaps Treated with Finasteride or Azelaic Acid.
Azelaic acid and finasteride can help preserve skin flaps after surgery by increasing BCL-2 protein and decreasing bax protein.
research The effect of low-intensity electromagnetic radiation of the EHF band and ozone therapy on the state of tissue blood flow in the skin flap
EHF radiation and ozone therapy together improve skin flap healing.
research Effect of Platelet-Rich Plasma (PRP) on Dermal Skin Flap Survival: An Experimental Study in Rats
This experimental study on 16 female Wistar rats investigated the effects of heterologous leukocyte-rich platelet-rich plasma (L-PRP) on the viability of random-pattern dorsal skin flaps. The study found that local application of L-PRP significantly improved flap survival by reducing necrosis compared to the control group. Specifically, Group B (L-PRP treated) exhibited lower mean necrosis (0.59) and no severe necrosis cases, while Group A (control) showed higher mean necrosis (0.82) with only mediocre/severe necrosis. The results suggest that L-PRP enhances flap viability without causing adverse reactions, indicating its potential feasibility for improving skin flap outcomes.
research Effect of Topically Applied Minoxidil on the Survival of Rat Dorsal Skin Flap
Minoxidil applied before and after surgery improves skin flap survival in rats.
research The Utility of De-epithelialization in Subcutaneous Skin Flap Transposition.
De-epithelialization reduces complications in subcutaneous skin flap procedures.
research ISCHEMIC SKIN FLAPS: WHAT TO USE TO SAVE THEM? A NARRATIVE REVIEW
Various substances, quitting smoking, and certain topical applications can enhance the survival of skin flaps used in surgery. Oxygen-free radicals play a role in tissue injury, but certain treatments can have beneficial effects.
research Fibonacci sequence ‘snail’ flap versus skin grafts in scalp reconstruction: a comparative study
The Fibonacci 'snail' flap heals faster and looks better than skin grafts for scalp reconstruction.
research Sodium Valproate Improves Skin Flap Survival via Gamma-Aminobutyric Acid and Histone Deacetylase Inhibitory System
Sodium valproate helps skin healing by affecting GABA and histone deacetylase.
research Tanshinone IIA pretreatment protects free flaps against hypoxic injury by upregulating stem cell-related biomarkers in epithelial skin cells
Tanshinone IIA helps protect skin tissue from low oxygen damage by boosting certain cell markers.
research Combination therapy profoundly improved skin flap survival by modulating KATP channels and nitric oxide
The combination of azelaic acid, minoxidil, and caffeine significantly increased the survival of skin flaps by affecting certain body channels and nitric oxide levels.
research Improvement of Tissue Survival of Skin Flaps by 5α-Reductase Inhibitors: Possible Involvement of Nitric Oxide and Inducible Nitric Oxide Synthase
5α-reductase inhibitors may help skin flaps survive better by affecting nitric oxide.
research Cell-Free Fat Extract (Ceffe) Combined with GelMA Hydrogel to Improve the Survival Rate of Random Skin Flaps in Mice
This study investigates the use of cell-free fat extract (Ceffe) encapsulated in gelatin methacrylate (GelMA) hydrogel to improve the survival rate of random skin flaps in mice. Ceffe, known for its bioactive compounds, was limited by quick leakage and short effectiveness when injected directly. By encapsulating Ceffe in GelMA, the study developed a stable release system that promotes angiogenesis and flap repair, as confirmed by various assays and histological analyses. The Ceffe@GelMA system demonstrated significant pro-repair activity, enhanced pro-angiogenic potential, and favorable biocompatibility, suggesting its therapeutic efficacy in preventing flap necrosis and representing a significant advancement in clinical treatment strategies.
research Prevention of unfavourable effects of cigarette smoke on flap viability using botulinum toxin in random pattern flaps: An experimental study
Botulinum toxin may help reduce skin flap damage caused by cigarette smoke.
research The Effect of Topical Minoxidil Pretreatment on Nonsurgical Delay of Rat Cutaneous Flaps: Further Studies
Minoxidil improved rat skin flap survival but was less effective than surgical methods.
research Local Flaps of the Head and Neck
The document concludes that local flaps are effective for reconstructive surgery in the head and neck, offering good skin match and function.
research The Potential Application of Exosomes as Therapeutic Agents, Carriers, and Biomarkers in Skin Diseases
Exosomes could revolutionize skin disease treatment and healing.
research Complex Scalp Reconstruction with Super Thin DIEP Free Flap
A super thin DIEP flap can effectively reconstruct scalp defects with good skin coverage and contour.
research Free skin grafts in dogs-A review
Skin grafts are a common, minimally invasive way to close wounds in dogs, but better methods are still being sought.
research Optimal placement of Burow's triangles for aesthetically pleasing repair of multiple defects using local flaps after tumor excision
The technique effectively repairs skin after tumor removal, maintaining appearance and function without complications.
research Flap Advancement Technique for Scalp Hair Preservation in Massive Cutis Verticis Gyrata
The flap advancement technique effectively treats severe scalp skin conditions, preserving hair and improving appearance.
research Dual transposition flaps for the reconstruction of large scalp defects
Technique effectively reconstructs large scalp defects with minimal hair loss and visible scarring.
research Aesthetic Management of External Skin Paddles Following Microvascular Reconstruction of the Head and Neck
Improve skin paddle appearance after head and neck reconstruction using tissue expansion, rearrangement, and flaps.
research Scalp reconstructive flaps
Choose the simplest, most fitting scalp reconstruction method for each patient's unique needs.
research Hair removal evaluated with a filterless flashlamp‐based system: a preliminary study in 10 patients
The filterless flashlamp-based system effectively delays hair regrowth and improves skin condition.
research Mesenchymal Stromal Cell-Conditioned Medium for Skin Diseases: A Systematic Review
The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.
research Interpolated Melolabial Flaps: Reconstruction of Alar and Columellar Units
Using cheek skin and cartilage grafts for nose reconstruction after skin cancer surgery can maintain shape and function but may require multiple surgeries and hair removal in men.
research Innovations in Skin and Soft Tissue Aging—A Systematic Literature Review and Market Analysis of Therapeutics and Associated Outcomes
Stem cell therapies show the most promise for anti-aging benefits.
research Hair Transplantation, Scalp Reduction, and Flap Rotation in Black Men
Hair loss surgeries like grafts, scalp reductions, and flap rotations can be effective for black men with proper technique adjustments.
research Light-Emitting Hair Follicles: Studying Skin Regeneration With In Vivo Imaging
Scientists developed tools to observe hair regeneration in real time and assess skin health, using glowing mice and light-controlled genes.