204 citations
,
February 2000 in “Current Medicinal Chemistry” Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
68 citations
,
March 2008 in “Experimental dermatology” The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
41 citations
,
November 2003 in “Annals of the New York Academy of Sciences” Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
6 citations
,
January 2023 in “International journal of molecular sciences” Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.
6 citations
,
September 2022 in “Vaccines” Some people developed alopecia areata after COVID-19 vaccination, but it's not caused by the vaccine and most improved with treatment.
1 citations
,
July 2016 in “Cosmetics” Black henna tattoos can cause severe allergies to hair and textile dyes, and there's a need for greater public awareness and regulation.
129 citations
,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
6 citations
,
December 2022 in “International Journal of Molecular Sciences” Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.
20 citations
,
June 2022 in “Molecules” Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.
3 citations
,
July 2024 in “Journal of Vascular Diseases” Ischemia-modified albumin can help diagnose ischemic conditions early, but better detection methods are needed.
2 citations
,
September 2025 in “Food Production Processing and Nutrition” Capsaicin offers health benefits and flavor but faces challenges in food use.
2 citations
,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.
November 2022 in “International Journal of Pharmaceutical and Bio-Medical Science” The herbal hair oil may improve hair shine and address hair issues, but its effectiveness is unclear.
May 2021 in “Research journal of topical and cosmetic sciences” TrichovitalsTM improved skin, hair, and nail health in adults after 12 weeks.
May 2018 in “Pakistan journal of nutrition” Feeding sheep up to 30% Leucaena leaf meal does not harm their blood metabolites and thyroid hormones.
7 citations
,
October 2012 in “PubMed” Triamcinolone regrows hair better but relapses more than anthralin.
May 2022 in “Голова и шея.” Essential oils can boost athletic performance by improving brain function and muscle relaxation.
January 2016 in “Skin appendage disorders” The document discusses various nail and hair disorders and their treatments.
506 citations
,
January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
474 citations
,
January 2012 in “Chemistry & biology” Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
144 citations
,
August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
53 citations
,
April 2021 in “Cell Host & Microbe” Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.
28 citations
,
July 2005 in “International Journal of Dermatology” Vitiligo is caused by the immune system attacking skin pigment cells.
26 citations
,
April 2023 in “Medicina” Platelet-rich plasma therapy improves oral lichen planus symptoms with few side effects.
24 citations
,
July 2017 in “Structure” FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.
23 citations
,
April 2016 in “American Journal of Pathology” The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.
1 citations
,
November 2023 in “iScience” A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
Hair RiseTM microemulsion effectively promotes hair growth and treats hair loss better than standard treatments.
August 2024 in “Asian Journal of Research in Chemistry” Repurposing existing drugs can improve cancer treatment but faces challenges.
April 2024 in “Pharmaceuticals” Bimatoprost helps with hair growth and eye conditions but can be costly and have side effects.