January 2018 in “Elsevier eBooks” 5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.
11 citations
,
January 2000 in “Der Hautarzt” Male hypogonadism affects skin and hair, causing thin skin, less hair, and skin reactions to treatment.
5 citations
,
April 2021 in “Journal of Endocrinological Investigation” Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.
Check hormone levels and blood counts before surgery in dogs with abnormal blood cell counts.
March 2025 in “Institutional Repositories DataBase (IRDB)” The testes significantly contribute to vitamin D metabolism and may affect male reproductive health and conditions like hair loss.
4 citations
,
May 2019 in “Biology open” Testosterone reduces heart damage and inflammation after injury.
May 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Testosterone significantly affects urination differences between male and female mice.
26 citations
,
March 2001 in “PubMed” Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.
1 citations
,
February 2017 in “Clinical Dermatology Open Access Journal” A rare benign tumor was found in a man's scrotum, highlighting the need for accurate diagnosis.
111 citations
,
May 2001 in “Human reproduction update” Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.
January 2025 in “International Journal Of Scientific Advances” Topical testosterone can cause acne-like skin changes.
April 2019 in “Journal of the Endocrine Society” A woman's severe male-like symptoms were caused by a rare, benign tumor in her ovary that produced male hormones.
9 citations
,
January 2017 in “Archives of biochemistry and biophysics” Testosterone raises blood pressure and changes kidney protein levels.
July 2023 in “The journal of sexual medicine” Anabolic-androgenic steroids harm male hormone levels, sperm, metabolism, and can cause acne, hair loss, and breast growth.
Testosterone's health effects are complex and not definitively understood.
70 citations
,
April 2014 in “Annales d'endocrinologie” New genes and pathways are important for testosterone production and male sexual development.
229 citations
,
March 2001 in “European journal of endocrinology” Testosterone levels influence male behaviors and physical traits, but this relationship is complex and influenced by both internal and external factors.
18 citations
,
June 2016 in “PeerJ” Testosterone increases certain kidney protein levels, potentially raising blood pressure.
5 citations
,
October 2014 in “Gynecological Endocrinology” Triptorelin helps evaluate hormone production in Sertoli-Leydig cell tumors.
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
June 2015 in “Sonography” Ultrasound is effective for diagnosing scrotal cysts, and prompt treatment is crucial to prevent severe complications.
4 citations
,
January 2013 in “PubMed” Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.
Finasteride impairs sperm quality and fertility in rats, even after stopping treatment.
Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.
January 1977 in “Case Reports in Medicine” Steroid cell tumors in the ovary are rare, can produce testosterone causing symptoms, and are mainly treated with surgery.
13 citations
,
January 2019 in “Endocrine journal” Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.
11 citations
,
June 2005 in “Postgraduate Medical Journal” Some infants temporarily grow scrotal hair, which usually disappears on its own without any health issues.
110 citations
,
October 2013 in “The Journal of Sexual Medicine” Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.
Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.
41 citations
,
March 2016 in “The Journal of Clinical Endocrinology & Metabolism” In STSD patients, the body compensates for low androgen levels by increasing another enzyme's activity.