research CAQ Corner: Basic concepts of transplant immunology
The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.
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240-270 / 1000+ results research The secret identities of TMPRSS2: Fertility factor, virus trafficker, inflammation moderator, prostate protector and tumor suppressor
TMPRSS2 helps viruses enter cells and protects the prostate from inflammation-related cancer.
research Toll-like receptor 4 (TLR4): new insight immune and aging
TLR4 is important in aging-related diseases and could be a new treatment target.
research The JAK/STAT signaling pathway: from bench to clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Selenium Compounds and Their Bioactivities: Molecular Mechanisms and Prospects for Functional Food and Therapeutic Applications
Selenium from plants is beneficial and safer for health.
research Cepharanthine Suppresses Herpes Simplex Virus Type 1 Replication Through the Downregulation of the PI3K/Akt and p38 MAPK Signaling Pathways
Cepharanthine effectively reduces Herpes Simplex Virus Type 1 by blocking certain cell pathways and promoting cell death.
research Trace element zinc and skin disorders
Zinc is important for skin health, and supplements can help treat various skin and hair disorders, but more research is needed for conditions like psoriasis and vitiligo.
research Association between Mesenchymal Stem Cells and COVID-19 Therapy: Systematic Review and Current Trends
Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.
research Internal peacekeepers and external mediators: A new model of peripheral immune tolerance involving regulatory T cells and mesenchymal stem cells
Regulatory T cells and mesenchymal stem cells work together to prevent immune system overreactions and tissue damage.
research Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
Bioprinting is improving skin models for better testing of skin diseases without using animals.
research Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin
Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.
research Hydrogel crosslinking modulates macrophages, fibroblasts, and their communication, during wound healing
Softer hydrogels help wounds heal better with less scarring.
research Therapeutic Potential of Brassinosteroids in Biomedical and Clinical Research
Brassinosteroids may be useful in treating cancer, infections, and other diseases.
research Advances in the human skin microbiota and its roles in cutaneous diseases
Balancing skin microbiota is crucial for healthy skin and treating skin diseases.
research IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes
A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
research Exploring the relationship between anastasis and mitochondrial ROS-mediated ferroptosis in metastatic chemoresistant cancers: a call for investigation
Targeting specific molecular pathways may improve treatments for chemoresistant cancers.
research Applications of Ultrasound-Mediated Gene Delivery in Regenerative Medicine
Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.
research A comprehensive genome-wide analysis for signatures of selection in goat (genus Capra) revealed new candidate genes for environmental adaptation and productive traits
Goat genes show adaptation to environments and traits like body development, with differences among cashmere, feral, and milk-producing goats.
research Nano-Enabled CRISPR-Cas Gene Editing for Cancer Therapeutics
Nanotechnology improves CRISPR-Cas9 delivery for cancer treatment, but challenges remain.
research New frontiers in CRISPR/Cas9 delivery systems delivery for gene editing
Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.
research Fibroblast growth factors: key players in regeneration and tissue repair
Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
research The RpoS Gatekeeper in Borrelia burgdorferi: An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity
RpoS helps Borrelia burgdorferi survive in hosts and adapt to different environments.
research The Skin and Inflamm-Aging
Aging skin causes inflammation that affects the whole body.
research Endogenous/exogenous stimuli‐responsive smart hydrogels for diabetic wound healing
Smart hydrogels can improve diabetic wound healing by adapting to wound conditions and providing controlled treatment.
research Follicular Fluid: A Powerful Tool for the Understanding and Diagnosis of Polycystic Ovary Syndrome
Analyzing follicular fluid can help predict and improve outcomes for women with PCOS undergoing fertility treatments.
research Nanomedicine-based immunotherapy for tissue regeneration
Nanomedicine-based immunotherapy shows promise in improving tissue repair and regeneration.
research Auditory Threshold Variability in the SAMP8 Mouse Model of Age-Related Hearing Loss: Functional Loss and Phenotypic Change Precede Outer Hair Cell Loss
Hearing decline in SAMP8 mice starts before outer hair cell loss and may be linked to other changes.
research Soluble CD83 improves and accelerates wound healing by the induction of pro-resolving macrophages
Soluble CD83 speeds up wound healing and reduces scarring.
research Use of Antiandrogens as Therapeutic Agents in COVID-19 Patients
Antiandrogens may help prevent or treat COVID-19 by blocking virus entry into cells.
research The role of glucose metabolism in wound healing: an overview
Glucose metabolism is crucial for wound healing but can delay healing in chronic wounds due to increased stress and inflammation.