January 2024 in “Women's health science journal” Hormonal imbalances are a key cause of missed menstrual periods in women.
February 2024 in “Pediatrics in review” A 15-year-old girl with missed periods was diagnosed with a pituitary disorder and treated with hormones and steroids.
21 citations
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September 2004 in “Fertility and Sterility” Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.
78 citations
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November 2008 in “Fertility and Sterility” Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.
May 2021 in “Journal of the Endocrine Society” The 18-year-old girl likely has a condition called müllerian agenesis, which caused her to not have a uterus and experience no menstrual periods.
Polycystic ovary syndrome (PCOS) affects about 10% of women, is often linked to obesity and family history, and can cause irregular periods, fertility issues, and other symptoms. It's usually managed with lifestyle changes, weight loss, and medication.
38 citations
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October 2006 in “Fertility and Sterility” The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.
October 2010 in “Reproductive Biomedicine Online” Women with pituitary adenomas often have reproductive issues, like irregular periods and trouble getting pregnant, but not always breast milk production without pregnancy.
October 2025 in “Česká gynekologie” Hyperprolactinemia is the most common cause of secondary amenorrhea, followed by drug use.
January 2026 in “Journal of Contemporary Studies in Epidemiology and Public Health” Women with PCOS often have severe PMS, but managing anemia and regular menstruation can help reduce symptoms.
4 citations
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January 2014 in “Dermatology” A woman with acne and baldness was found to have a rare ovarian condition but successfully had a child through fertility treatment.
3 citations
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April 1977 in “PubMed” The treatment improved acne, seborrhoea, and hirsutism, with some side effects like spotting and nervousness.
Exercising women with irregular periods have lower thyroid hormone levels and less body fat.
July 2025 in “Journal of Advanced Nursing” Older first-time mothers experience more postpartum symptoms and distress than younger ones.
October 2011 in “InTech eBooks” Menstrual cycles can be irregular for women of childbearing age.
November 2025 in “Journal of Rangpur Medical College” Oligomenorrhea is the strongest predictor of PCOS severity.
5 citations
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September 2023 in “Clinical Endocrinology” Polymenorrhoea should be included in PCOS diagnostic criteria due to similar metabolic issues.
77 citations
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March 2004 in “Human Reproduction” Women with irregular periods and/or excessive body hair are more likely to have polycystic ovaries, and this condition is linked to higher health risks.
December 2022 in “Journal of Pharmaceutical Negative Results” Late onset of first period and irregular development of sexual traits in teenage girls can lead to poorer reproductive health.
1 citations
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February 2024 in “Gynecological Endocrinology” Medroxyprogesterone acetate is as effective as oral contraceptives for resuming ovulation in women with PCOS.
September 2023 in “Kerala Journal of Ayurveda” Ayurvedic treatment helped a woman with PCOS resume regular periods and improve symptoms without side effects.
January 2011 in “Yearbook of Endocrinology”
November 2022 in “Journal of the Endocrine Society” A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.
2 citations
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November 2020 in “Fertility Research and Practice” The survey helps identify menstrual irregularities and excess male hormones, aiming to detect conditions like Polycystic Ovary Syndrome.
3 citations
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December 2016 in “PubMed” Menstrual abnormalities in PCOS women may not greatly affect their metabolic and hormonal profile.
4 citations
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February 2011 in “Annals of internal medicine” The document concludes that Polycystic Ovary Syndrome is a commonly underdiagnosed hormonal disorder in women, diagnosed by specific criteria.
Treatment improved symptoms in a woman with HAIR-AN syndrome.
July 2022 in “International journal of medical science and clinical invention” Women with irregular periods should be checked for PCOS and treated early to prevent complications, with birth control pills helping to manage symptoms.
7 citations
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May 2024 in “Acta Obstetricia Et Gynecologica Scandinavica” Severe menstrual issues in PCOS women signal higher risk for heart and metabolic problems.
6 citations
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November 1997 in “International Journal of Dermatology” Women with acne and irregular periods had higher active testosterone levels, which could suggest the usefulness of antiandrogen treatment.