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May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
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January 2017 in “Elsevier eBooks” The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.
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November 2015 in “Indian Journal of Clinical Biochemistry” The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.
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August 2015 in “Current Sexual Health Reports” 5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.
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January 2015 in “Journal of nutrition & health” Fish oil improves skin health in people with diabetes and high cholesterol.
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September 2013 in “Elsevier eBooks” Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
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December 2012 in “I P Pavlov Russian Medical Biological Herald” Finasteride increases P-glycoprotein activity in the liver and kidney.
Finding functions for unknown GPCRs is hard but key for making new drugs.
April 2026 in “Inflammopharmacology” This study explores the antifibrotic potential of Punica granatum ethanolic leaf extract (PGEL) against skin scleroderma, focusing on oxidative stress, inflammation, and the TGF-β1/Snail 1/p-Smad 3 signaling pathway. In a rat model with 24 subjects, PGEL was administered at doses of 200 and 400 mg/kg, resulting in reduced oxidative stress and inflammation markers, such as IL-17 A, TNF-α, and MMP-9. PGEL also downregulated fibrotic markers like COL1A1 and Snail 1, and decreased TGF-β1 and p-Smad 3 levels, leading to improved dermal thickness and collagen fiber arrangement. The study suggests that PGEL, rich in compounds like ellagic acid and catechin-3-O-gallate, may offer therapeutic benefits for skin fibrosis by targeting inflammation, extracellular matrix production, and oxidative stress.
April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” Red light exposure can slow aging in mice by improving fat metabolism.
Testosterone pellet therapy may better address hormone imbalances in aging by focusing on local hormone production and symptom relief.
March 2026 in “American Journal of Clinical Dermatology” Cancer survivors need better skin care to improve their quality of life.
March 2026 in “Frontiers in Cell and Developmental Biology” Vascular endothelial cells may significantly influence skin stem cells, but more research is needed.
February 2026 in “Journal of Dermatology and Skin Science” Dermatologists are key in detecting and managing OCD and BFRBs by working with psychiatrists.
February 2026 in “Frontiers in Medical Technology” Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
January 2026 in “Frontiers in Bioscience-Landmark” Araliadiol protects skin cells from damage by boosting antioxidant defenses.
January 2026 in “BioScience Trends” UV radiation causes skin aging by damaging cells and triggering harmful processes.
November 2025 in “International Journal of Innovative Research in Technology” Hormones significantly affect hair growth and loss, requiring personalized treatment.
November 2025 in “Frontiers in Endocrinology” Apigenin and ellagic acid may help manage PCOS symptoms.
October 2025 in “Frontiers in Molecular Biosciences” Bruce Ames's work has greatly influenced research on genetics, aging, and health, inspiring ongoing studies on mitochondria and longevity.
September 2025 in “BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY” Better supportive care is needed to manage chemotherapy side effects.
July 2025 in “International Journal of Pharmaceutical Sciences Review and Research” Balanced selenium intake from wheat is crucial for preventing hair loss.
January 2025 in “Fitoterapia” Signaling pathways are key targets for developing effective drugs.
January 2025 in “Journal of Medical Biochemistry” Superoxide dismutases help balance cell stress and may aid cancer treatment.
December 2024 in “Deleted Journal” New therapies show promise for wound healing, but more research is needed for safe, affordable options.
July 2024 in “Journal Of Stem Cell Research” Mesenchymal stem cells improve skin appearance and structure in dermatology and aesthetic medicine.
June 2024 in “Georgetown medical review” Finasteride treats hair loss but may cause low libido, erectile issues, and depression.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.
Minoxidil and nebivolol can help prevent aortic aging in diabetic mice.
March 2024 in “Revista Ciências da Saúde CEUMA” Testosterone increases sexual behavior in female capuchin monkeys.