349 citations
,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
316 citations
,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
265 citations
,
July 2012 in “Cell” The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.
245 citations
,
October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
204 citations
,
February 2000 in “Current Medicinal Chemistry” Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
184 citations
,
December 2018 in “Nature Communications” Researchers created human hair follicles using a new method that could help treat hair loss.
156 citations
,
March 2022 in “Exploration” Bioactive inorganic particles-based biomaterials show promise for improving skin wound healing.
153 citations
,
August 2002 in “Dermatologic Surgery” Follicular Unit Extraction (FUE) is a less invasive hair transplant method with minimal scarring, suitable for about 60% of patients, especially those needing fewer grafts and quicker recovery.
100 citations
,
August 2022 in “Microbial Cell Factories” Balancing skin microbiota is crucial for healthy skin and treating skin diseases.
72 citations
,
September 1997 in “Dermatologic Surgery” Careful planning and patient counseling can lead to excellent hair transplant results, often in one or two sessions.
67 citations
,
January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
67 citations
,
September 1997 in “Dermatologic Surgery” The document concludes that good cosmetic outcomes in hair transplantation depend on the surgeon's artistic skill and careful planning.
66 citations
,
December 2014 in “Nature Communications” Fibroblasts can be turned into melanocytes for potential skin treatments.
66 citations
,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
59 citations
,
July 2015 in “Journal of Immunology” Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.
50 citations
,
December 2007 in “Journal of Biomedical Materials Research Part B Applied Biomaterials” Keratin-gelatin films improve skin graft success in dogs.
49 citations
,
March 2014 in “Journal of Investigative Dermatology” Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.
49 citations
,
June 2009 in “Seminars in Cutaneous Medicine and Surgery” The cosmetic industry should adapt to the varied beauty standards of ethnic groups and offer specialized treatments.
48 citations
,
December 2022 in “Biomolecules” 3D bioprinting shows promise for creating advanced skin for healing wounds and reducing animal testing.
48 citations
,
March 2021 in “Frontiers in Cell and Developmental Biology” Human mesenchymal stem cells show promise for treating skin diseases, but more research is needed to improve treatments.
48 citations
,
April 2008 in “Human Molecular Genetics” Progerin affects cell shape but not hair or skin in mice.
47 citations
,
November 2012 in “Pharmaceutical research” Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
46 citations
,
October 2023 in “Science Advances” 3D bioprinting can now create skin with hair-like structures for medical use.
45 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” Using sharp tools and the right techniques in hair transplant surgery leads to less damage to hair follicles.
45 citations
,
December 2007 in “The FASEB journal” There are two types of stem cells in rodent hair follicles, each with different keratin proteins.
43 citations
,
October 2003 in “Journal of The American Academy of Dermatology” Hair transplanting is a useful, often overlooked treatment for female pattern hair loss.
41 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” FUE provides minimal scarring and quick recovery in hair transplantation, and surgeons not using it may lag in technology.
40 citations
,
August 2014 in “Journal of Nanoparticle Research” Silver nanoparticles in gel form can effectively heal wounds.
37 citations
,
October 2017 in “Advanced drug delivery reviews” The review suggests that there are various treatments to help restore skin color after severe burns.
34 citations
,
July 2010 in “Expert Opinion on Drug Delivery” The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.