489 citations
,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
218 citations
,
September 2012 in “Gastroenterology” Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
89 citations
,
August 2013 in “PloS one” Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
82 citations
,
May 2010 in “PLoS neglected tropical diseases” Secondary syphilis in Cali, Colombia, shows high Treponema pallidum presence and challenges in early diagnosis, needing better public health strategies.
72 citations
,
July 2022 in “Frontiers in Systems Biology” Modern lifestyles harm beneficial microbes, affecting health.
70 citations
,
May 2023 in “Molecules” Ginkgo biloba has health benefits but also contains toxic compounds, driving interest in its use in medicine and food.
63 citations
,
September 2020 in “Frontiers in Microbiology” Probiotics show promise for health benefits but need more research to understand how they work.
54 citations
,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
53 citations
,
July 2021 in “International Journal of Molecular Sciences” Geranium pyrenaicum extracts show potential for cancer, antiviral, and enzyme inhibition treatments.
49 citations
,
October 2024 in “Frontiers in Immunology” Polysaccharides boost immunity and could help prevent and treat diseases.
43 citations
,
September 2021 in “Nutrients” Persimmons offer health benefits and can be used in new products and sustainable applications.
41 citations
,
February 2021 in “Translational research” Non-coding RNAs could help detect and treat radiation damage.
40 citations
,
January 2022 in “Frontiers in Chemistry” The patch speeds up deep wound healing.
25 citations
,
June 2024 in “Pharmaceutics” Scaffold-based drug delivery systems improve oral cancer treatment by targeting drugs directly to cancer cells, reducing side effects.
24 citations
,
March 2020 in “Cells” Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
17 citations
,
January 2025 in “Journal of Nanobiotechnology” Bacterial extracellular vesicles could revolutionize regenerative medicine but need safety improvements.
14 citations
,
September 2023 in “Foods” Microfluidics can create precise, efficient delivery systems for food and cosmetics, but scaling up is challenging.
14 citations
,
June 2009 in “Journal of veterinary internal medicine” High doses of albendazole can be deadly for alpacas.
13 citations
,
December 2005 in “Traffic” Syntaxin 9 helps in transporting and signaling of the EGF receptor in skin and stomach cells.
11 citations
,
June 2025 in “Polymers” Polysaccharide-based niosomes improve drug delivery and show promise in cancer therapy but face challenges in scalability and stability.
9 citations
,
August 2022 in “Frontiers in Pharmacology” Kangfuxin (KFX) extract speeds up wound healing and improves skin regeneration.
9 citations
,
June 2016 in “Stem cells” Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.
8 citations
,
July 2025 in “Gels” Functionalized hydrogels can help heal tissues and fight infections by delivering beneficial bacteria and antimicrobials.
8 citations
,
September 2024 in “Food Science & Nutrition” β-Sitosterol may help prevent heart disease, cancer, and diabetes, but more human studies are needed.
8 citations
,
January 2021 in “Fermentation” Probiotics and synbiotics might help manage hirsutism by improving insulin resistance.
6 citations
,
July 2025 in “Pharmaceuticals” Marine biomaterials show promise for drug delivery and wound healing.
6 citations
,
December 2023 in “Journal of Clinical Medicine” Abnormal growth factor metabolism may link psoriasis and metabolic syndrome, and obesity can affect psoriasis treatment effectiveness.
6 citations
,
February 2022 in “JAAD International” Higher doses of isotretinoin may lead to more hair loss.
6 citations
,
December 2015 in “International journal of immunopathology and pharmacology” AE can have varied symptoms and genetic causes, but zinc therapy helps.
5 citations
,
July 2025 in “Nutrients” Nanotechnology can improve food safety, nutrition, and health, but safety and regulation challenges need addressing.