research Characterization of DNA Methylation and Screening of Epigenetic Markers in Polycystic Ovary Syndrome
Altered DNA methylation may be a marker for Polycystic Ovary Syndrome.
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600-630 / 1000+ results research Perspective Chapter: Beyond BMI – Rethinking Obesity Assessment in Women’s Health
BMI is not enough for assessing obesity in women; use more personalized tools.
research 144 Evaluation of contamination and quantification of drug penetrations studies using Quantitative Mass Spectrometry Imaging
QMSI effectively maps and quantifies drug distribution in skin tissues.
research Skin as a Metabolic Organ: Dermatologic Markers of Morbid Obesity and Their Role in Risk Stratification and Treatment Monitoring
Skin changes in obesity can indicate metabolic issues but aren't reliable for assessing risk or monitoring treatment.
research Hypothalamic lipid metabolism and the control of food intake
The VMH AMPK-SNS-BAT axis may help treat cachexia and obesity.
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes
Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.
research Green and Emerging Microextraction Strategies for Bioanalytical Determination of Hormones: Trends, Challenges, and Applications
Microextraction techniques improve hormone testing while being environmentally friendly.
research Simultaneous Analysis of Biomarkers in Human Hair for Evaluating Chronic Tobacco Smoke Exposure and Stress/Relaxation Using Online In-Tube Solid-Phase Microextraction Coupled with Liquid Chromatography–Tandem Mass Spectrometry
A new method can quickly and accurately measure tobacco exposure and stress using a small hair sample.
research Determination of steroid hormones in human hair as a retrospective biomarker with HPLC-MS/MS
A new method accurately measures long-term hormone levels in hair.
research Bioconversion, Pharmacokinetics, and Therapeutic Mechanisms of Ginsenoside Compound K and Its Analogues for Treating Metabolic Diseases
Ginsenoside compound K shows promise for treating metabolic diseases like diabetes and obesity.
research Metabolic aging and cutaneous markers of metabolic syndrome: a narrative review
Skin conditions can signal underlying metabolic issues and increased health risks.
research The Transcriptomics and Epigenomics of Hair Follicles
research Food Deprivation-induced Expression of Minoxidil Sulfotransferase in the Hypothalamus Uncovered by Microarray Analysis
Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
research Analysis of Methyltestosterone and Testosterone Propionate in Dried Blood Spots After Transdermal Application
The method effectively detects MeT and TP in dried blood spots after cream application.
research COMPATIBILITY OF BIOMAGNETIC PROFILES FOUND IN LIVING MATTER BY CROSS SPECIES DEMONSTRATION
New techniques can record electromagnetic fields in hair follicles for potential medical use.
research Radyoterapinin Metastatik Meme Kanseri Hücrelerindeki Mitokondri İlişkili Yolaklar Üzerine Etkisi
Radiotherapy affects mitochondrial-related genes in metastatic breast cancer cells.
research Optimal processing for proteomic genotyping of single human hairs
The method improved hair analysis for better forensic identification.
research A rapid screening LC‐MS/MS method based on conventional HPLC pumps for the analysis of low molecular weight xenobiotics: application to doping control analysis
A quick method was developed to detect banned substances in urine for doping control.
research Screening and confirmation methods of the major urinary metabolite of finasteride–carboxy-finasteride by liquid chromatography–mass spectrometry and liquid chromatography–tandem mass spectrometry
New methods can detect finasteride's major urinary metabolite in urine for up to 49 hours.
research Gene profile analysis of colorectal cancer cell lines by cDNA macroarray
Colorectal cancer's ability to spread is due to changes in many genes, not just one.
research The multifaceted role of hair as a biospecimen: recent advances in precision medicine and forensic science
Hair analysis is valuable for health and forensics but faces challenges like growth variability and contamination.
research Global Single-Cell Sequencing Landscape of Adipose Tissue of Different Anatomical Site Origin in Humans
Different parts of the body's fat tissue have unique cell types and characteristics, which could help treat chronic wounds.
research Exploring the Gut Microbiome and Metabolome in Individuals with Alopecia Areata Disease
Alopecia Areata is linked to specific gut bacteria and metabolites, indicating a complex gut microbiome.
research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids
The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
research Serum and hair steroid profiles and their associations with body composition in adolescence.
Androgen levels are more linked to body size in boys than girls.
research Demonstrating the potential of untargeted hair proteomics for personalized biomarkers in stress-associated disorders
Hair proteomics could be a promising non-invasive way to identify stress-related disorders.
research Composition, isolation, identification and function of adipose tissue-derived exosomes
Adipose tissue-derived exosomes help regulate metabolism and may aid in disease treatment.
research Development of a new gas chromatography–mass spectrometry (GC–MS) methodology for the evaluation of 5α-reductase activity
A new method was developed to accurately measure enzyme activity related to prostate health.
research Metabolic syndrome – a new definition and management guidelines A joint position paper by the Polish Society of Hypertension, Polish Society for the Treatment of Obesity, Polish Lipid Association, Polish Association for Study of Liver, Polish Society of Family Medicine, Polish Society of Lifestyle Medicine, Division of Prevention and Epidemiology Polish Cardiac Society, “Club 30” Polish Cardiac Society, and Division of Metabolic and Bariatric Surgery Society of Polish Surgeons
The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.