research Small Molecule Wnt Pathway Modulators from Natural Sources: History, State of the Art and Perspectives
Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
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180-210 / 1000+ resultsresearch 5-Fluorouracil induces hair loss by inhibiting β-catenin signaling and angiogenesis
5-Fluorouracil causes hair loss by blocking signals needed for hair growth.
research Wnt Signaling and Aging-Related Heart Disorders
Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
research Empagliflozin targeting STAT3/Akt/Nrf2 axis promoting diabetic wound healing in rat model
Empagliflozin helps heal diabetic wounds in rats by reducing inflammation and oxidative stress.
research The Role of Pannexin 3 in Bone Biology
Pannexin 3 is important for bone formation and the development of bone cells.
research Signal integrator function of CXXC5 in Cancer
CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
research Antioxidant and Antiproliferative Activity of Finasteride against Glioblastoma Cells
High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.
research Phytochemicals for Hair Health Targeting Growth Signaling Molecules in Hair Follicular Stem Cells: A New Strategy for Hair Growth
Natural extracts may promote hair growth with fewer side effects than conventional treatments.
research PSAT1 regulates hair follicle growth and stem cell behavior in cashmere goats
PSAT1 is key for hair growth and stem cell function in cashmere goats.
research Bioinformatic analysis of gene expression data reveals Src family protein tyrosine kinases as key players in androgenetic alopecia
Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.
research Deficiency of Formyl Peptide Receptor 2 Retards Hair Regeneration by Modulating the Activation of Hair Follicle Stem Cells and Dermal Papilla Cells in Mice
Lack of FPR2 slows hair growth by affecting hair cell activity.
research Transcriptome Sequencing Reveals Differences between Primary and Secondary Hair Follicle-derived Dermal Papilla Cells of the Cashmere Goat (Capra hircus)
Primary and secondary hair follicle cells in Cashmere goats have different gene expressions affecting hair growth and size.
research Nitrogen‐Boosted H 2 O 2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration
A new nanozyme using EGCG and L-arginine boosts hair growth by safely increasing beneficial oxidative stress.
research HNG, A Humanin Analogue, Promotes Hair Growth by Inhibiting Anagen-to-Catagen Transition
HNG helps hair grow by keeping hair in the growth phase longer.
research Integrin signalling regulates YAP/TAZ to control skin homeostasis
YAP and TAZ are crucial for skin cell growth and repair.
research miR-370-3p Inhibited the Proliferation of Sheep Dermal Papilla Cells by Inhibiting the Expression of SMAD4
miR-370-3p slows sheep hair cell growth by blocking SMAD4.
research Exosomal miRNA-218–5p derived from low-passage dermal papilla cells modulates hair follicle growth and development
Exosomal miRNA-218-5p promotes hair growth and development.
research Fermented Yeast Complex Extract Promotes Hair Regrowth by Decreasing Oxidative Stress
Fermented Yeast Complex Extract helps regrow hair by reducing oxidative stress and inflammation.
research Developmental signals in skin morphogenesis
Key signals like Wnt and β-catenin are crucial for skin and hair development, with potential for treating skin disorders.
research Regulatory mechanisms of LGR4 on cancer and cancer stem cell properties
Targeting LGR4 may help treat cancer by reducing cancer stem cell traits and drug resistance.
research Exosomes in trichology: A literature review
Exosome therapy could help with hair loss, but more research and regulation are needed.
research Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance
Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.
research Pyruvate Kinase M2 Role in Cardiovascular Repair
PKM2 is a promising target for heart repair and regeneration.
research Scars or Regeneration?—Dermal Fibroblasts as Drivers of Diverse Skin Wound Responses
Understanding fibroblasts can help create treatments to reduce scars and improve healing.
research FGF20 Secreted From Dermal Papilla Cells Regulate the Proliferation and Differentiation of Hair Follicle Stem Cells in Fine‐Wool Sheep
FGF20 is essential for hair follicle stem cell growth and development in fine-wool sheep.
research Stem Cell-Derived and Plant-Derived Exosomes: Promising Therapeutics for Skin Healing and Regeneration
Stem cell and plant exosomes may help heal and regenerate skin.
research Conditional Knockout in Mice Reveals the Critical Roles of Ppp2ca in Epidermis Development
PP2Acα is essential for proper hair and skin development.
research β‐Sitosterol—Dietary sources and role in cancer and diabetes management
β-Sitosterol may help prevent heart disease, cancer, and diabetes, but more human studies are needed.
research Exploring the Role of Dermal Sheath Cells in Wound Healing and Fibrosis
Dermal sheath cells play a key role in wound healing and could impact fibrosis.
research miR-22 promotes stem cell traits via activating Wnt/β-catenin signaling in cutaneous squamous cell carcinoma
miR-22 helps skin cancer grow and spread by activating specific cell signals.