People with early onset hair loss (Androgenetic Alopecia) in Ile-Ife, Nigeria, have significantly lower iron levels compared to those with adult-onset hair loss.
February 2018 in “PubMed” Society's pressure to have children later in life favors genes that increase the risk of early baldness in male offspring.
December 2006 in “8th European Congress of Endocrinology incorporating the British Endocrine Societies” Men with early hair loss and hormonal changes like PCOS could be the male equivalent of PCOS, not linked to metabolic syndrome.
November 2024 in “Revista de Investigación y Educación en Ciencias de la Salud (RIECS)” A 7-year-old girl developed early pubic hair growth without other puberty signs, diagnosed as isolated premature pubarche.
The herbal hair conditioner with custard apple and curry leaves improves hair smoothness and manageability.
8 citations
,
January 2013 in “BioMed Research International” Age, gender, and hair loss affect scalp characteristics differently in young Caucasian adults.
2 citations
,
December 2025 in “Annals of Medicine” This review explores the complex relationship between cellular senescence and polycystic ovary syndrome (PCOS), highlighting how mechanisms like replicative senescence, stress-induced premature senescence, and immunoinflammatory responses contribute to PCOS. Key features of senescence, such as cell cycle arrest, oxidative stress, and DNA damage, are linked to impaired follicular development and increased pregnancy complications in PCOS patients, particularly those who are obese, hyperandrogenic, or insulin-resistant. The study suggests that senolytic and senomorphic drugs, which target senescent cells and their effects, could be promising treatments for PCOS. Understanding these mechanisms may offer new insights into PCOS pathogenesis and support the development of anti-senescence therapies.
February 2019 in “Yeni Üroloji Dergisi” Premature hair whitening or loss may indicate a risk for erectile dysfunction.
January 2014 in “International Journal of Clinical Medicine” Premature aging increases the risk of immune problems and autoimmune diseases.
November 2024 in “Journal of Investigative Dermatology” Paclitaxel chemotherapy causes premature aging and damage to hair follicles, potentially leading to permanent hair loss.
January 2008 in “Catalunya música: Revista musical catalana” Tooth loss can cause premature gray hair due to less chewing.
51 citations
,
October 2019 in “Cells” Baricitinib reduces inflammation and improves cell health in premature aging cells.
1 citations
,
May 2022 in “International journal of molecular sciences” Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.
February 2025 in “International Journal of Molecular Sciences” Altered lipid pathways in diabetic women may cause premature greying.
April 2023 in “Journal of Investigative Dermatology” Ganoderma lucidum extract can potentially reduce stress-induced hair loss by slowing down premature hair aging and removing harmful substances.
29 citations
,
January 2020 in “Frontiers in endocrinology” Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.
7 citations
,
January 2024 in “Cancer Research Communications” TAp63 and NRF2 work together to manage oxidative stress, preventing premature aging and aiding skin functions.
November 2001 in “CRC Press eBooks” Hair loss from telogen effluvium happens when a disturbance or imbalance causes hair to fall out prematurely.
237 citations
,
February 2016 in “Science Translational Medicine” The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
64 citations
,
November 2012 in “EMBO reports” Lamins are vital for cell survival, organ development, and preventing premature aging.
Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.
4 citations
,
March 2022 in “Ghana Medical Journal” Hair greying is common in Lagos, starting around age 30, more in males than females.
April 2025 in “International Journal For Multidisciplinary Research” A rare ovarian tumor caused early puberty in a 3-year-old girl.
81 citations
,
February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
March 2026 in “Wiadomości Lekarskie” Psychological stress speeds up skin aging.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Herbal remedies may help manage alopecia areata hair loss.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Herbal remedies might help treat alopecia areata, but more research is needed.
June 2023 in “GALENICAL Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh” Telogen effluvium is a form of hair loss caused by various factors and requires identifying the cause for proper treatment.
April 2023 in “Journal of Investigative Dermatology” The study found that aging hair follicle stem cells change behavior, leading to hair loss, but drugs targeting these cells may help restore hair growth.
77 citations
,
August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which are reversible with treatment.