research A Current Diagnostic and Therapeutic Challenge: Tinea Capitis
Early recognition and treatment of tinea capitis are crucial to prevent severe scalp issues and prolonged therapy.
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900-930 / 1000+ resultsresearch Addressing Knee Osteoarthritis Pathology Through Platelet‐Rich Plasma Treatment: A Comprehensive Review
PRP injections improve knee function in osteoarthritis.
research Association between DNA Methylation in the Core Promoter Region of the CUT-like Homeobox 1 (CUX1) Gene and Lambskin Pattern in Hu Sheep
DNA methylation likely doesn't cause different lambskin patterns in Hu sheep.
research The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring
PBMCsec can help reduce and improve thick skin scars.
research Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis?
Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.
research Diseases of the Canine Prostate Gland
The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.
research Perspective Chapter: Repurposing Natural Products to Target COVID-19 – Molecular Targets and New Avenues for Drug Discovery
Natural products might help treat COVID-19, but current drugs like hydroxychloroquine haven't worked.
research Collagen Involvement in Health, Disease, and Medicine
Collagen is crucial for health and treating certain diseases, and supplements can improve skin, nails, and hair conditions.
research Pathological Skin Scarring: From Mechanism to Targeted Local Therapy
Pathological skin scarring, including hypertrophic scars and keloids, arises from dysregulated wound healing processes involving excessive inflammation and mechanical tension, leading to fibroblast differentiation and disorganized collagen deposition. The review identifies key signaling pathways, such as TGF-β/Smad and TNF-α/NF-κB, as therapeutic targets and highlights a novel treatment using atorvastatin delivered via a keratin hydrogel derived from human hair. This approach offers a sustainable, localized anti-fibrotic therapy. Combination therapies are suggested to be more effective than monotherapies, although recurrence remains a challenge. The document also discusses genetic predispositions, various current treatments, and emphasizes the need for further research to optimize therapies for scar-free healing.
research Chirality Effect on Physical and Biological Properties of Peptide-Based Hydrogels
Chirality influences the structure, strength, and biological uses of peptide-based hydrogels.
research Histopathological investigation of wound healing activities of Lucilia sericata Larva and Achillea sintenisii extract combinations in diabetic rat wound model
The combination of Lucilia sericata larva secretions and Achillea sintenisii extract significantly improves wound healing in diabetic rats.
research Mesenchymal Stem Cell-Derived Extracellular Vesicles and Plant-Derived Nanovesicles as Cell-Free Therapies for Thermal Burn Healing: A Systematic Review of Preclinical Evidence and Delivery Strategies
Vesicle-based therapies from stem cells and plants improve burn healing and could be safe, scalable alternatives to cell transplants.
research The Genus Astragalus Species as an Emerging Source of Bioactive Phytochemicals: A Review of Dermatological and Cosmetic Applications
Astragalus plants may improve skin health and have anti-aging benefits.
research Baseline Neutrophil-to-Lymphocyte Ratio Stratifies Early Trichoscopic Response to Platelet-Rich Plasma–Based Regimens in Non-Scarring Alopecia: A Real-World Cohort with Internal Validation Using an Interpretable Neural Network
A high neutrophil-to-lymphocyte ratio may predict poor response to hair loss treatment.
research Bio-Nanovesicle-Based Approaches for Hair and Skin Regeneration: An Updated Concise Review
Bio-nanovesicles could improve hair and skin regeneration by delivering important molecules to repair and heal.
research Nano-Enabled CRISPR-Cas Gene Editing for Cancer Therapeutics
Nanotechnology improves CRISPR-Cas9 delivery for cancer treatment, but challenges remain.
research Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerative Healing
Reprogramming adult fibroblasts may enable scar-free healing.
research Clinical Applications of Extracellular Vesicles: Promises and Pitfalls
Extracellular vesicles show promise for medical use but face challenges in standardization and safety.
research Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerating Healing
Mimicking fetal wound environments may enable scarless healing in adults.
research Peptide-Based Approaches for Pain Relief and Healing in Wounds
Topical peptides may offer safer, effective pain relief and healing for wounds.
research Stimuli-responsive hydrogels for radiation-induced skin injury: from passive barriers to autonomous drug delivery systems
Advanced hydrogels can autonomously deliver drugs to treat radiation skin injuries, but challenges remain for clinical use.
research Oral Centella asiatica Extract Attenuates UVB-Induced Skin Photoaging via Antioxidant, Anti-Inflammatory, and Extracellular Matrix-Preserving Effects in Hairless Mice
Centella asiatica extract taken orally can reduce skin aging from UVB exposure.
research Reprogramming of Aged Dermal Papilla Cells in Vitro: In Silico Insight into the Biomarkers of Hair Growth and Tissue Repair
Aging dermal papilla cells can be reprogrammed for potential hair growth and skin repair.
research The systemic wrinkled skin phenotype involves aberrant expression and variation of genes related to the oxidative stress and extracellular matrix in Xiang pigs
Wrinkled skin in Xiang pigs is linked to gene changes related to oxidative stress and the extracellular matrix.
research Platelet-Rich Plasma (PRP): Molecular Mechanisms, Actions and Clinical Applications in Human Body
PRP shows promise in healing and regeneration but needs standardized protocols for consistent results.
research Stem Cell Secretome for Skincare: Of Cell Types, Exosomes, Extracellular Vesicles, and Soluble Fractions
Adipose mesenchymal stem cells are best for skincare because they reduce inflammation and are safe and effective.
research Do Syrian conflict survivors show novel chronic cutaneous sequelae from chlorine gas exposure: A case report and literature review
Chlorine gas exposure can cause long-term skin issues.
research A skin organoid-based infection platform identifies an inhibitor specific for HFMD
NSC167409 can effectively inhibit the virus causing hand, foot, and mouth disease.
research Mealworm-Derived Protein Hydrolysates Enhance Adipogenic Differentiation via Mitotic Clonal Expansion in 3T3-L1 Cells
Mealworm protein helps fat cell development and may aid in metabolic health and hair growth.
research Current Insight of Peptide-Based Hydrogels for Chronic Wound Healing Applications: A Concise Review
Peptide-based hydrogels are promising for healing chronic wounds effectively.