295 citations
,
June 2009 in “Science” Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.
113 citations
,
July 2020 in “International Journal of Molecular Sciences” Allogenic ASCs and ECM transplants are safe and effective for tissue regeneration.
81 citations
,
September 2005 in “The American journal of pathology” Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
53 citations
,
April 2016 in “Stem cell research & therapy” LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.
45 citations
,
August 2018 in “Haematologica” Macrophage iron release is crucial for hair growth and wound healing.
42 citations
,
December 2011 in “The journal of immunology/The Journal of immunology” RANKL causes lymph nodes to grow by making certain cells multiply.
40 citations
,
March 2018 in “Aesthetic Surgery Journal” New treatment combining PRP and SVF increases hair density in 6-12 weeks for androgenetic alopecia patients.
36 citations
,
July 2022 in “Stem Cell Research & Therapy” SVF may improve nanofat treatment for acne scars, but more research is needed.
30 citations
,
July 2017 in “Stem cells and cloning” SVF-enhanced adipose transplantation shows potential as a hair loss treatment.
20 citations
,
September 2019 in “Journal of Cosmetic Dermatology” SVF-PRP therapy effectively reverses hair loss effects.
20 citations
,
July 2019 in “Stem cell investigation” Combining SVF and PRP speeds up wound healing.
19 citations
,
October 2023 in “Bioengineering” tSVF is effective for treating inflammation-related conditions, with centrifugation being the best method for isolation.
19 citations
,
April 2021 in “Stem Cell Research & Therapy” SVF cell transplantation improves skin regeneration safely.
13 citations
,
June 2020 in “Stem Cells International” A substance from a specific gel helped to grow hair effectively in mice, suggesting it could potentially be used to treat hair loss in humans.
13 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose tissue shows promise for hair regrowth, but more research is needed to confirm best practices and effectiveness.
11 citations
,
August 2023 in “Regenerative Therapy” SVF is safe and effective, but research quality is low; new guidelines are proposed to improve future studies.
11 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
11 citations
,
June 2018 in “Sexual medicine reviews” Stromal Vascular Fraction might help with male sexual dysfunction, but more research is needed to confirm its safety and effectiveness.
10 citations
,
January 2012 in “Journal of Oncology” The surrounding tissue plays a crucial role in the growth and spread of skin cancer.
8 citations
,
January 2011 in “Experimental and Therapeutic Medicine” Stromal cells in melanoma promote tumor growth and spread.
7 citations
,
June 2024 in “Skin Research and Technology” Combining treatments significantly reduces dark circles and wrinkles better than nanofat alone.
3 citations
,
December 2020 in “Journal of the turkish academy of dermatology” Stromal Vascular Fraction treatment increases hair density and thickness, making it a safe and effective treatment for Androgenetic Alopecia.
2 citations
,
December 2019 in “Nanoscience and Nanotechnology Letters” SVF and PRP promote hair growth by boosting specific proteins in the Wnt/β-catenin pathway.
1 citations
,
October 2025 γδ T cells help control tissue scarring and blood vessel growth in response to foreign objects.
1 citations
,
December 2023 in “PubMed” Combining PRP and SVF speeds up burn healing by controlling inflammation.
1 citations
,
December 2022 in “Archives of Dermatological Research” SVF injections improve hair growth and reduce hair loss in people with androgenic alopecia.
April 2026 in “Stem Cell Research & Therapy” This systematic review evaluated the efficacy and safety of five regenerative medicine modalities for androgenetic alopecia (AGA) across 20 clinical studies with 724 patients. Conditioned media (CM) was the most studied, showing improvements in hair density and thickness, especially when combined with minoxidil. Platelet-rich fibrin (PRF) provided rapid and consistent results, particularly when used with hair transplantation. Stromal vascular fraction (SVF) showed outcomes comparable to or better than platelet-rich plasma (PRP). Extracellular vesicles (EV) and stem cell therapies demonstrated significant hair density improvements and follicle regeneration. All approaches reported only mild, transient adverse events. Despite promising results, the review highlights the need for larger, standardized trials to optimize regenerative strategies for AGA.
Lack of certain cells causes abnormal nipple development and nursing failure.
January 2025 in “Journal of Carcinogenesis” Stromal vascular fraction and topical minoxidil both improve hair growth similarly, but SVF offers a better treatment experience.
January 2025 in “Haematology International Journal” These ovarian conditions cause high testosterone levels.