research Low serum zinc concentration is associated with low serum testosterone but not erectile function
Low zinc levels are linked to low testosterone but not to sexual problems.
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research Letter to the Editor on “COVID-19 Infection in Men on Testosterone Replacement Therapy”
The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.
research Testosterone in Transgender Population
research Testosterone replacement in the setting of Finasteride therapy: a therapeutic dilemma
research Systemic testosterone induces structural, immunological, and sex steroid receptor changes in human XX skin
This study investigated the effects of systemic testosterone on XX skin, particularly in transgender individuals undergoing gender-affirming hormone treatment. Analyzing discarded skin samples from surgeries, researchers found that testosterone-treated skin showed a 2.77-fold increase in androgen receptor-positive cells, elevated estrogen and progesterone receptor-positive cell counts, a 43% reduction in CD45 positive immune cells, and a 2.93-fold increase in collagen density in the dermis. In the epidermis, there was a reduction in progesterone receptor-positive cells and increased fibronectin expression. These changes suggest that testosterone-treated XX skin develops characteristics similar to male skin, driven by altered sex steroid receptor expression, immune cell infiltration, and structural organization. The study emphasizes the need for further research to understand the mechanisms of testosterone-induced skin remodeling and its impact on surgical outcomes.
research Intratesticular platelet-rich plasma (PRP) application to improve testicular development, hemodynamic and testosterone in male lambs
PRP injections may slightly improve testicular development in male lambs.
research Effect of the ethanol extract of Syzygium aromaticum (clove) leaves on the lipid profile and body weight in testosterone-induced benign prostatic hyperplasia rats
Clove leaf extract lowers bad cholesterol and increases good cholesterol while also increasing body weight.
research Early Dissecting Cellulitis of the Scalp Following Repeated Microinfusion of Medication Into the Skin in a Patient With Androgenetic Alopecia and Long-Term Exogenous Testosterone Use: A Case Report
Microinfusion therapy and testosterone use may cause scalp inflammation, requiring early recognition and treatment.
research The Effect of Finasteride on Serum Cortisol and testosterone Levels in Rats
Finasteride lowers cortisol and raises testosterone levels in rats.
research Development and Validation of A C57BL/6 Mouse Model of Androgenetic Alopecia Through Testosterone Propionate Induction
A mouse model was created to study hair loss similar to humans.
research APPLICATIONS AND SAFETY OF TESTOSTERONE CREAMS: A SYSTEMATIC REVIEW OF TOPICAL FORMULATIONS, CLINICAL EFFICACY, AND POTENTIAL RISKS
Testosterone creams and gels can be effective but have serious risks and should be used only with medical supervision.
research Cutaneous Manifestations and Their Relationship with Serum Testosterone and DHEAS Levels in Women with Polycystic Ovary Syndrome: A Cross‑Sectional Clinical Study
Hirsutism and acne indicate high androgen levels in women with PCOS, and early treatment can improve symptoms and quality of life.
research Cutaneous Manifestations and Their Relationship with Serum Testosterone and DHEAS Levels in Women with Polycystic Ovary Syndrome: A Cross‑Sectional Clinical Study
Hirsutism and acne indicate high androgen levels in women with PCOS, suggesting early treatment can help.
research Understanding the Secular Decline in Testosterone: Mechanisms, Consequences, and Clinical Perspectives
Lifestyle changes and environmental strategies can help address declining testosterone levels.
research Hepatoprotective and anti-hyperplastic effects of silver nanoparticles biosynthesised using aqueous extracts of M. scaber : Insights from acetaminophen and testosterone experimental models
Silver nanoparticles from Mitracarpus scaber protect the liver and reduce prostate enlargement.
research Protective role of agomelatine via modulation of TLR4/NF-κB: NLRP3/IL-1β signaling pathways in testosterone-induced benign prostatic hyperplasia in rats
Agomelatine may help reduce benign prostatic hyperplasia by blocking certain inflammatory pathways.
research Coconut oil works as a gonadal feedback testosterone booster and increases pituitary aromatase (cyp19a1b) expression levels in fugu (Takifugu rubripes)
Coconut oil boosts testosterone but doesn't fully trigger reproductive maturity in pufferfish.
research The Role of Vitamin D and Testosterone Levels with Hair Loss among Females with Coronavirus Disease
Higher testosterone and lower Vitamin D levels are linked to hair loss in female COVID-19 patients.
research An Unusual Case of Elevated Testosterone: When Testosterone by Dialysis Saves the Day
Equilibrium dialysis can accurately measure testosterone levels when lab results are inconsistent.
research Khảo sát tác dụng kích thích mọc lông của cao ethanol toàn phần chiết xuất từ bột lá Tía tô (Perilla frutescens L. (Britt)) trên chuột nhắt Swiss albino rụng lông do testosteron
Perilla leaf extract effectively stimulates hair growth like minoxidil.
research Effect of 3-Beta Hydroxysteroid Dehydrogenase on Serum Testosterone Level in Obese Women With Polycystic Ovary Syndrome
3βHSD2 is not useful for diagnosing PCOS.
research TESTOSTERONE-INDUCED ANDROGENETIC ALOPECIA MICE MODEL: A PRELIMINARY STUDY
A testosterone-induced hair loss model in mice was successfully created for future research and treatment testing.
research A Natural Inhibitor, 1′S-1′-Acetoxychavicol Acetate, Against Testosterone-Induced Alopecia via NADPH Oxidase Regulation
1′S-1′-Acetoxychavicol acetate may help treat hair loss by reducing oxidative stress.
research Dermatology Residency Education in Treatment of Testosterone-Induced Acne Vulgaris and Androgenic Alopecia in Transmasculine Individuals: A Cross-Sectional Survey of Academic Dermatologists
Dermatology trainees lack standardized guidelines and education for treating testosterone-induced skin conditions in transmasculine individuals.
research Phenyl Propanoid 1’s-1′-Acetoxychavicol Acetate Protects Against Testosterone-Induced Alopecia by Inhibiting Nadph Oxidase
ACA from Alpinia galanga may prevent testosterone-related hair loss.
research The Serum Evaluation of Sex Hormones Including DHEAs, DHT, Testosterone in Oral Lichen Planus Patients
Oral lichen planus is not linked to sex hormone levels.
research Mendelian randomization studies of testosterone exposure: A systematic review
Testosterone's health effects are complex and not definitively understood.
research Effect of Cuscuta reflexa Extract in Mitigating Testosterone-Induced Benign Prostatic Hyperplasia in Rats: Targeting Inflammation and Oxidative Stress
Cuscuta reflexa extract may help treat benign prostatic hyperplasia by reducing inflammation and oxidative stress.
research Evaluating Testosterone and Dehydroepiandrosterone Sulfate (DHEA-S) as Biomarkers for Male Androgenetic Alopecia
Higher testosterone and DHEA-S levels may be linked to male pattern baldness.
research Dysregulation of Leukaemia Inhibitory Factor (LIF) Signalling Pathway by Supraphysiological Dose of Testosterone in Female Sprague Dawley Rats During Development of Endometrial Receptivity
High testosterone levels can harm fertility by disrupting the LIF signaling pathway in the uterus.