research Biomaterials Mimicking Mechanobiology: A Specific Design for a Specific Biological Application
Polymers can be designed to mimic natural cell environments for medical uses.
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60-90 / 675 resultsresearch Cellular and Molecular Mechanisms of Wound Repair: From Biology to Therapeutic Innovation
Advancements in wound healing aim to improve personalized treatments and enhance healing outcomes.
research Research Advances in Therapeutic Strategies and Drug Delivery Systems for Pathological Scars
New drug delivery systems show promise in effectively treating pathological scars.
research Cell fate decisions: emerging roles for metabolic signals and cell morphology
Metabolic signals and cell shape influence how cells develop and change.
research MicroRNA-205 promotes hair regeneration by modulating mechanical properties of hair follicle stem cells
MicroRNA-205 helps hair regrow by making hair follicle stem cells less stiff.
research The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair
TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.
research Mechanisms of Impaired Skeletal Muscle Regeneration and Therapeutic Approaches in Aging and Chronic Disease
Aging and chronic diseases impair muscle repair, but integrated therapies like exercise and gene editing may help.
research Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration
Biomaterials can help heal wounds without scars and regenerate skin features.
research Scars or Regeneration?—Dermal Fibroblasts as Drivers of Diverse Skin Wound Responses
Understanding fibroblasts can help create treatments to reduce scars and improve healing.
research Wnt Signaling Is Deranged in Asthmatic Bronchial Epithelium and Fibroblasts
Wnt signaling is disrupted in asthma, affecting cell growth and inflammation.
research From structural resilience to cell specification — Intermediate filaments as regulators of cell fate
Intermediate filaments are crucial for cell differentiation and stem cell function.
research Prediction and Demonstration of Retinoic Acid Receptor Agonist Ch55 as an Antifibrotic Agent in the Dermis
Ch55 may help reduce skin scarring and fibrosis.
research Wnt Signaling Across Adult Skin Mini-Organs: Interfollicular Epidermis, Hair Follicle, and Nail—Implications for Disease and Regeneration
Wnt signaling is crucial for skin, hair, and nail health and regeneration.
research Toward a Unifying Hypothesis for Redesigned Lipid Catabolism as a Clinical Target in Advanced, Treatment-Resistant Carcinomas
Targeting lipid metabolism can help treat advanced, resistant cancers.
research Fibroblasts: Origins, definitions, and functions in health and disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
research [Retracted] Fibroblasts in Scar Formation: Biology and Clinical Translation
Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.
research Ontogeny of Skin Stem Cells and Molecular Underpinnings
Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.
research Biliary fibrosis is an important but neglected pathological feature in hepatobiliary disorders: from molecular mechanisms to clinical implications
Biliary fibrosis is crucial in liver diseases and understanding it can help prevent and treat these conditions.
research Marine-Derived Polysaccharide Nanofibers for Wound Healing: Mechanistic Rationale, Biofabrication Strategies, and Translational Barriers
Marine-derived polysaccharide nanofibers could improve wound healing but face challenges in becoming widely used.
research Life before and beyond blistering: The role of collagen XVII in epidermal physiology
Collagen XVII is vital for skin structure, hair stem cell support, and skin cell regulation.
research Epigenetic Mechanisms, Assessment and Therapeutics of Epidermal Stem Cells in Skin Aging
Epigenetic changes in skin cells contribute to aging, but targeting these changes may offer new antiaging treatments.
research From basic biology to engineered therapies: the keratinocyte stem cell playbook
Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
research Hardwiring Stem Cell Communication through Tissue Structure
The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
research The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function
Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
research Surface-induced mechano-regulation of macrophages: emerging strategies for immunotherapy
Mechanical surface cues can control macrophage behavior for better immunotherapy and tissue healing.
research Spatiotemporal dynamics of mammalian wound healing
Understanding wound healing involves coordinating different phases and areas to improve treatment strategies.
research Wedelolactone, a natural coumestan with multiple pharmacological effects
Wedelolactone may help treat inflammation, infections, cancer, bone loss, and organ damage.
research Recent advances and challenges in 3D bioprinting for skin tissue regeneration
3D bioprinting shows promise for skin regeneration but needs more development to fully replicate natural skin.
research Hair follicle organoids: advances in construction, applications, and translational challenges
Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
research Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.