40 citations
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December 2016 in “Journal of Ovarian Research” Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
March 2026 in “Physical Education Health and Social Sciences” Combining cinnamon and inositol improves hormone and metabolism issues in women with PCOS.
December 2023 in “Journal of the Endocrine Society” Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
1 citations
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March 2025 in “Portuguese Journal of Dermatology and Venereology” Many women with melasma also have metabolic syndrome.
May 2026 in “Reviews in Endocrine and Metabolic Disorders” The review addresses the impact of the global obesity epidemic on reproductive health, emphasizing the need for effective weight loss interventions during gestation to improve maternal and fetal health outcomes. It explores surgical and pharmacological strategies, with a focus on incretin-based therapies like GLP-1 receptor agonists and GIP dual agonists, which may enhance reproductive function and adapt to metabolic changes in pregnancy. These changes involve insulin signaling, lipid metabolism, and inflammatory regulation. The review also highlights the long-term risks of maternal obesity, such as increased likelihood of childhood obesity, underscoring the importance of managing gestational weight gain.
July 2022 in “Fayoum University Medical Journal” Different types of PCOS affect metabolic syndrome and pregnancy rates differently.
January 2026 in “International Journal of Gynaecology Sciences” The document discusses the proposal to redefine Polycystic Ovary Syndrome (PCOS) as Polyendocrine Metabolic Ovarian Syndrome (PMOS) to better capture its complex pathophysiology and systemic metabolic effects. The current focus on ovarian morphology in PCOS diagnosis often overlooks significant metabolic dysfunctions, such as insulin resistance and cardiovascular risks, leading to delayed and inappropriate treatment. The review emphasizes the need for a comprehensive approach to management, including personalized nutrition, lifestyle changes, hormonal therapy, psychological support, and multidisciplinary care, to improve long-term health outcomes for women affected by this condition.
December 2023 in “ANNALS OF ABBASI SHAHEED HOSPITAL AND KARACHI MEDICAL & DENTAL COLLEGE” Spexin levels are lower in PCOS patients and linked to metabolic and hormonal issues.
60 citations
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February 2010 in “Gynecological Endocrinology” Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.
67 citations
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February 2010 in “Acta Obstetricia et Gynecologica Scandinavica” Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.
11 citations
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November 2017 in “Hong Kong Medical Journal” Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.
4 citations
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August 2018 in “Clinical Endocrinology” Women with PCOS have more insulin resistance and are more likely to have heart-related health issues, with insulin resistance being a bigger factor than β-cell problems.
3 citations
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June 2025 in “Drug Design Development and Therapy” Targeting glycolysis may help treat PCOS by improving insulin sensitivity and ovarian function.
April 2026 in “Metabolites” Chronic skin diseases and metabolic syndrome are linked by shared inflammation pathways.
December 2025 in “Frontiers in Endocrinology” High chromogranin A levels are linked to obesity and inflammation in polycystic ovary syndrome.
November 2025 in “Basic and Clinical Andrology” Male relatives of women with PCOS show similar health issues, suggesting a male version of the condition.
February 2022 in “Mediators of Inflammation” Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.
November 2025 in “BMC Endocrine Disorders” The TT/DHT ratio may help identify PCOS patients with severe metabolic issues.
4 citations
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July 2024 in “Journal of Reproduction & Infertility” Fenugreek can help with PCOS symptoms, but metformin is more effective overall.
January 2026 in “International Journal of Reproductive BioMedicine (IJRM)” Probiotics may help improve health markers in women with PCOS.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Early recognition and comprehensive management of PCOS can prevent long-term health issues.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Early recognition and comprehensive management of PCOS can prevent long-term health issues.
Women with PCOS have hormonal imbalances and increased central obesity, highlighting the need for early detection and management.
16 citations
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March 2015 in “Wiener Klinische Wochenschrift” Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.
January 2024 in “Biomarker Insights” Certain genetic variants may increase the risk of developing PCOS.
May 2018 in “University Library - University of Saskatchewan (University of Saskatchewan)” A pulse-based diet with exercise improved PCOS health more than another diet, but benefits didn't last long-term.
June 2025 in “Research Square (Research Square)” HAIR-AN syndrome mainly affects obese women and can be improved with early diagnosis and treatment using insulin-sensitizing agents.
5 citations
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January 2019 in “cIRcle (University of British Columbia)” A high fiber, low glycemic diet, exercise, and stress management can help reduce PCOS symptoms.
70 citations
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February 2009 in “Biological Trace Element Research” 12 citations
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October 2018 in “Journal of Mind and Medical Sciences” An unhealthy lifestyle increases the risk of metabolic syndrome.