research Long-acting microneedle formulations
Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
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research Abstracts from the 55th European Society of Human Genetics (ESHG) Conference: e-Posters
Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.
research The Multiple Consequences of Obesity
Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.
research Long-Term Effects of Sirolimus on Human Skin TSC2-Null Fibroblast‒Like Cells
Sirolimus can reduce tumor cell size in TSC-related skin tumors, but continuous treatment is needed to maintain benefits.
research Biochemistry of Vitamin B: Metabolic Regulations, Deficiency Disorders and Emerging Therapeutic Strategies
Vitamin B is essential for metabolism and health, and new therapies are improving its effectiveness.
research Catecholaminergic neurons boost fibroblast osteogenic activity in keloid
Targeting catecholaminergic signaling may help treat keloid scars.
research Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS)
PDE5 inhibitors cause earlier adverse events in BPH treatment, requiring careful monitoring.
research Temporal Dynamics of Endothelium After Radiation Injury Reveal a Transient Pro-Angiogenic Capillary Subpopulation Associated with Skin Repair
A temporary capillary cell type helps skin repair after radiation by promoting blood vessel growth.
research Hyperinnervation inhibits organ-level regeneration in mammalian skin
Reducing nerve growth can help skin regenerate after birth.
research Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis
A specific group of immune and skin cells may cause chronic inflammation in atopic dermatitis.
research Perifollicular Elastolysis: A Systematic Review of Clinical Characteristics, Histopathology, and Therapeutic Outcomes
Perifollicular elastolysis is poorly understood, with limited treatment options and inconsistent results.
research Enhancing Cancer Therapy with Hyperthermia: Synergistic Effects with Natural Compounds and Conventional Treatments
Combining hyperthermia with natural compounds and conventional treatments improves cancer therapy effectiveness and reduces side effects.
research Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury
Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
research Aesthetically relevant symptoms of menopause transition: Impact and approach to management
Managing menopause symptoms like skin changes and hair thinning involves hormone therapy, procedures, and skincare, with emotional support being important.
research Research Advances in Therapeutic Strategies and Drug Delivery Systems for Pathological Scars
New drug delivery systems show promise in effectively treating pathological scars.
research Robotic Horizons in Plastic Surgery: A Look Toward the Future
Robotic technology in plastic surgery shows promise but needs more research and cost reduction for wider use.
research RNA modifications: molecular orchestrators of wound healing
RNA modifications help heal wounds and could lead to new treatments.
research Unraveling Translational Insights into Systemic Multi-Organ Toxicity of Cytosine Arabinoside (Ara-C): A Systematic Review of Preclinical Animal Evidence
Cytarabine can cause multiple organ toxicities, especially neurotoxicity, but better research methods are needed to fully understand and predict these effects.
research An Anti-Inflammatory and Pro-Angiogenic Porous Aloe Polysaccharide-Collagen Dressing Accelerates Wound Healing
The aloe-collagen dressing speeds up wound healing effectively.
research Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
Bioprinting is improving skin models for better testing of skin diseases without using animals.
research Immortality Reconsidered: Clinical Challenges at the Frontier of Plastic Surgery
Advancements in regenerative science and longevity research can improve healthspans, but must be balanced with ethics and safety.
research T H 1 effector CD4 T cells rely on IFN-γ production to induce alopecia areata
IFN-γ production by CD4 T cells is crucial for causing alopecia areata.
research The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling and Disease
The skin microenvironment significantly affects hair growth and loss, offering potential treatment avenues.
research Cannabidiol in Skin Health: A Comprehensive Review of Topical Applications in Dermatology and Cosmetic Science
CBD may help with skin and hair issues, but more research is needed.
research Development and Evaluation of Nanoemulgel Loaded with Minoxidil
The new minoxidil nanoemulgel may treat hair loss more effectively with fewer side effects.
research Revolutionizing psoriasis care: Microneedle innovations in treatment and diagnosis
Microneedles offer a promising, less invasive way to treat and monitor psoriasis.
research Single‐Cell RNA Sequencing Highlights a Contribution of Human Amniotic Mesenchymal Stem Cells‐Derived Exosomes to Androgenetic Alopecia
Human amniotic stem cell exosomes may effectively treat hair loss by promoting hair regrowth.
research Resolution of experimental malaria-associated acute respiratory distress syndrome is Alox12 independent and shows residual inflammation
Resolving malaria-related lung issues doesn't rely on Alox12 and leaves some inflammation.
research Deciphering gene regulatory programs in mouse embryonic skin through single-cell multiomics analysis
HT-scCAT-seq helps understand gene regulation in embryonic skin development.
research The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury
Serine is vital for hair follicle stem cells to balance hair growth and skin repair.